Berlin's neighborhoods (Kieze) each have distinct personalities. Stay in Mitte for classic sightseeing, Kreuzberg or Neukölln for food and nightlife, Prenzlauer Berg for family-friendly cool.
First-timer pick
Mitte — walkable to Brandenburg Gate, Museum Island, Reichstag.
Best neighborhoods
Mitte
$$$Walk: Excellent
Central, historic, government + museum
First-timersMuseum tripsShort stays
Pros
Museum Island, Brandenburg Gate, Reichstag on foot
S-Bahn hub
Best luxury hotels
Cons
Corporate feel in parts
Less local nightlife
Nearby: Museum Island · Brandenburg Gate · Berlin Cathedral
Kreuzberg (36)
$$Walk: Great
Multicultural, Turkish market, graffiti-cool
NightlifeFoodiesYounger travellers
Pros
Best döner + Turkish food in Europe
Legendary nightlife (Berghain nearby)
U-Bahn everywhere
Cons
Loud on weekends
Some blocks still scruffy
Nearby: East Side Gallery · Görlitzer Park · Turkish Market on Maybachufer